C4733
BID, Caspase-8-cleaved from mouse
≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Size/SKU | Availability | Price |
|---|---|---|
50 μg | Check Cart for Availability | $940.00 |
About This Item
$940.00
Check Cart for Availability
recombinant
expressed in E. coli
Quality Segment
assay
≥95% (SDS-PAGE)
form
buffered aqueous solution
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
mouse ... Bid(12122)
General description
Mouse BID cleaved with caspase-8 generates the amino-terminal fragment (amino acids 1-59, 7 kDa) and the carboxy-terminal fragment (amino acids 60-195, 15 kDa). On size exclusion chromatography cleaved BID elutes at 27 kDa indicating that the fragments remain associated.
Biochem/physiol Actions
Caspase-8-cleaved BID relocates from the cytosol to the outer mitochondrial membrane where its interaction with Bak alters mitochondrial membrane permeability.
Physical form
0.2 μm filtered solution in 25 mM HEPES, pH 7.5, and 0.1 M KCl.
Analysis Note
Measured by its ability to induce cytochrome c release from isolated mouse liver mitochondria.
1 of 1
This Item | |||
|---|---|---|---|
| recombinant expressed in E. coli | recombinant - | recombinant expressed in E. coli (C-terminal histidine tagged) | recombinant expressed in E. coli (C-terminal histidine-tagged) |
| assay ≥95% (SDS-PAGE) | assay - | assay ≥90% (SDS-PAGE) | assay ≥85% (SDS-PAGE) |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 200 |
| form buffered aqueous solution | form - | form buffered aqueous solution | form buffered aqueous glycerol solution |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| shipped in dry ice | shipped in wet ice | shipped in dry ice | shipped in dry ice |
Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.