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C4733

BID, Caspase-8-cleaved from mouse

≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution

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50 μg
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$940.00

About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
MFCD03456214

$940.00

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recombinant

expressed in E. coli

Quality Segment

200

assay

≥95% (SDS-PAGE)

form

buffered aqueous solution

UniProt accession no.

P70444

shipped in

dry ice

storage temp.

−20°C

Gene Information

mouse ... Bid(12122)

General description

Mouse BID cleaved with caspase-8 generates the amino-terminal fragment (amino acids 1-59, 7 kDa) and the carboxy-terminal fragment (amino acids 60-195, 15 kDa). On size exclusion chromatography cleaved BID elutes at 27 kDa indicating that the fragments remain associated.

Biochem/physiol Actions

Caspase-8-cleaved BID relocates from the cytosol to the outer mitochondrial membrane where its interaction with Bak alters mitochondrial membrane permeability.

Physical form

0.2 μm filtered solution in 25 mM HEPES, pH 7.5, and 0.1 M KCl.

Analysis Note

Measured by its ability to induce cytochrome c release from isolated mouse liver mitochondria.

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AB10002C1224MAB4708
BID, Caspase-8-cleaved from mouse ≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution

Sigma-Aldrich

C4733

BID, Caspase-8-cleaved from mouse

Anti-mouse BID cleavage (59/60) site specific Antibody Chemicon®, from rabbit

Sigma-Aldrich

AB10002

Anti-mouse BID cleavage (59/60) site specific Antibody

Caspase 3 human ≥85% (SDS-PAGE), recombinant, expressed in E. coli (C-terminal histidine-tagged), buffered aqueous glycerol solution, ≥1.0 units/mg protein

Sigma-Aldrich

C1224

Caspase 3 human

Anti-Caspase 8 Antibody, clone 1-1-37 clone 1-1-37, Chemicon®, from mouse

Sigma-Aldrich

MAB4708

Anti-Caspase 8 Antibody, clone 1-1-37

description

≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution

description

Chemicon®, from rabbit

description

≥85% (SDS-PAGE), recombinant, expressed in E. coli (C-terminal histidine-tagged), buffered aqueous glycerol solution, ≥1.0 units/mg protein

description

clone 1-1-37, Chemicon®, from mouse

assay

≥95% (SDS-PAGE)

assay

-

assay

≥85% (SDS-PAGE)

assay

-

recombinant

expressed in E. coli

recombinant

-

recombinant

expressed in E. coli (C-terminal histidine-tagged)

recombinant

-

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

100

form

buffered aqueous solution

form

-

form

buffered aqueous glycerol solution

form

-

shipped in

dry ice

shipped in

wet ice

shipped in

dry ice

shipped in

wet ice

Gene Information

mouse ... Bid(12122)

Gene Information

mouse ... Bid(12122)

Gene Information

human ... CASP3(836)

Gene Information

human ... CASP8(841)

Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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