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Monoclonal Anti-Cytokeratin Peptide 4 antibody produced in mouse

Name: Monoclonal Anti-Cytokeratin Peptide 4 antibody produced in mouse
Brand: SIGMA
Price: 568 USD
Availability: InStock

clone 6B10, ascites fluid

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0.2 mL	Available to ship TODAYfromMILWAUKEE	$568.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD00211841

Conjugate:

unconjugated

Clone:

6B10, monoclonal

Application:

ARR, IF, IHC (f), IHC (p), WB

Citations:

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Properties

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

6B10, monoclonal

mol wt

antigen 59 kDa

contains

15 mM sodium azide

species reactivity

rabbit, feline, hamster, goat, guinea pig, human, canine, sheep

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, immunohistochemistry (frozen sections): suitable, indirect immunofluorescence: 1:300 using formalin-fixed, paraffin-embedded sections of human or animal tissue, microarray: suitable, western blot: suitable

isotype

IgG1

UniProt accession no.

P19013

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KRT4(3851)

Description

General description

Cytokeratins are intermediary filaments that are expressed during epithelial development. Cytokeratin-4 is largely found in non-epidermal, stratified epithelial tissues such as larynx, pharynx, vagina, exocervix and epiglottis among several others . Cytokeratin-4 has been implicated in Streptococcus agalactiae infection and genetic mutations in Cytokeratin-4 have been linked to white sponge naevus . Monoclonal Anti-Cytokeratin Peptide 4 antibody is specific for cytokeratin 4 in goats, hamsters, guinea pigs, cats, sheep, humans, rabbits, and dogs. The antibody weakly stains ciliated pseudostratified epithelium of bronchi. Ducts of skin sweat glands and prostate are focally stained by the antibody. Some endocervical columnar cells may also react with the antibody. This antibody is reactive with methanol or acetone fixed frozen sections, and with protease-digested formalin fixed paraffin embedded human tissues. Embedded methacarn fixed material can also be used for cytokeratin 4 demonstration.

Immunogen

cytokeratin from human esophagus.

Application

Monoclonal Anti-Cytokeratin Peptide 4 antibody is suitable for use in a broad range of immunoassays such as immunohistochemistry (frozen or formalin-fixed, paraffin-embedded sections), immunoblot, dot blot, and indirect immunofluorescence (1:300 using formalin-fixed, paraffin-embedded sections of human or animal tissue). The antibody may also be used for western blot and microarray.

Biochem/physiol Actions

The antibody reacts with non-cornifying squamous epithelium (e.g., exocervix, esophagus and cornea). Ciliated pseudostratified epithelium of bronchi is weakly stained. Ducts of sweat glands and prostate are focally stained. The antibody may react with some endocervical columnar cells.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	SAB1410738	C1399	C8541
Sigma-Aldrich C5176 Monoclonal Anti-Cytokeratin Peptide 4 antibody produced in mouse	Sigma-Aldrich SAB1410738 Anti-KRT4 antibody produced in rabbit	Sigma-Aldrich C1399 Anti-Cytokeratin Peptide 18 antibody, Mouse monoclonal	Sigma-Aldrich C8541 Monoclonal Anti-Cytokeratin Peptide 18 antibody produced in mouse
description clone 6B10, ascites fluid	description purified immunoglobulin, buffered aqueous solution	description clone KS-B17.2, purified from hybridoma cell culture	description clone CY-90, ascites fluid
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source mouse	biological source rabbit	biological source mouse	biological source mouse
clone 6B10, monoclonal	clone polyclonal	clone KS-B17.2, monoclonal	clone CY-90, monoclonal
Gene Information human ... KRT4(3851)	Gene Information human ... KRT4(3851)	Gene Information human ... KRT18(3875)	Gene Information human ... KRT18(3875)
antibody form ascites fluid	antibody form purified immunoglobulin	antibody form purified from hybridoma cell culture	antibody form ascites fluid
species reactivity rabbit, feline, hamster, goat, guinea pig, human, canine, sheep	species reactivity human	species reactivity human	species reactivity wide range

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Storage Class

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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