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C8791

Monoclonal Anti-Cytokeratin Peptide 14 antibody produced in mouse

Name: Monoclonal Anti-Cytokeratin Peptide 14 antibody produced in mouse
Brand: SIGMA

clone CKB1, ascites fluid

Synonyme(s) :

Anti-CK14, Anti-EBS1, Anti-EBS1A, Anti-EBS1B, Anti-EBS1C, Anti-EBS1D, Anti-EBS3, Anti-EBS4, Anti-K14, Anti-NFJ

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A propos de cet article

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD00162249

Conjugate:

unconjugated

Clone:

CKB1, monoclonal

Application:

IF, IHC (f), IHC (p)

Citations:

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Propriétés

biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

CKB1, monoclonal

contains

15 mM sodium azide

species reactivity

human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, immunohistochemistry (frozen sections): suitable, indirect immunofluorescence: 1:200 using methacarn-fixed, paraffin-embedded human tissue sections

isotype

IgM

UniProt accession no.

P02533

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KRT14(3861)

Description

General description

Monoclonal Anti-Cytokeratin Peptide 14 (mouse IgM isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Keratin 14 (KRT14) is expressed in keratinocytes and localized to the basal epidermal layer. The gene is mapped to human chromosome 17q21 and encodes an intermediate filament.

Immunogen

human callus keratins.

Application

Monoclonal Anti-Cytokeratin Peptide 14 antibody produced in mouse has been used in indirect immunofluorescence or immunoperoxidase techniques.

Biochem/physiol Actions

Keratin 14 (KRT14) is associated with maintaining cellular stability. Mutation in the KRT14 gene leads to epidermolysis bullosa simplex, a genetic disorder. It is known to promote angiogenesis, cell migration and proliferation in cancer cells.

The antibody reacts with myoepithelial cells in various organs (parotid, submandibular, mammary, prostate, and sweat glands) as well as with the basal layer of certain squamous epithelium (exocervical, laryngeal epithelium).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Cet article	SAB5500124	C0791	C5176
Sigma-Aldrich C8791 Monoclonal Anti-Cytokeratin Peptide 14 antibody produced in mouse	Sigma-Aldrich SAB5500124 Anti-Keratin 14 antibody, Rabbit monoclonal	Sigma-Aldrich C0791 Monoclonal Anti-Cytokeratin Peptide 13 antibody produced in mouse	Sigma-Aldrich C5176 Monoclonal Anti-Cytokeratin Peptide 4 antibody produced in mouse
Gene Information human ... KRT14(3861)	Gene Information human ... KRT14(3861)	Gene Information human ... KRT13(3860)	Gene Information human ... KRT4(3851)
species reactivity human	species reactivity human (tested)	species reactivity human	species reactivity rabbit, feline, hamster, goat, guinea pig, human, canine, sheep
clone CKB1, monoclonal	clone SP53, monoclonal	clone KS-1A3, monoclonal	clone 6B10, monoclonal
biological source mouse	biological source rabbit	biological source mouse	biological source mouse
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form ascites fluid	antibody form affinity isolated antibody	antibody form ascites fluid	antibody form ascites fluid

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Classe de stockage

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c