D0443
Sustine 470
Synonym(s):
1,6-α-D-Glucan 6-glucanohydrolase
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| Size/SKU | Availability | Price |
|---|---|---|
50 mL | Estimated to ship onAugust 21, 2026fromMILWAUKEE | $117.00 |
250 mL | Available to ship TODAYfromMILWAUKEE | $277.00 |
About This Item
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-803-9
MDL number:
$117.00
Estimated to ship onAugust 21, 2026Details
General description
A product of Novozymes Corp.
Dextranase is generated by many microorganisms, including bacteria, filamentous fungi, and yeast.
Application
Dextranase from Chaetomium erraticum has been used:
- in microcarrier dissolution to produce multicellular 3D spheroids for drug discoveryPMID 25012393
- in in vitro digestion of extracellular polysaccharide (EPS) from the bacterial isolatesPMID 26710215
- in a study to investigate the immobilization of dextranase
- to investigate the optimization of process conditions for enzymatic modification of alternan
Biochem/physiol Actions
Dextranase is an endodextranase that hydrolyzes α-(1,6)-glycosidic linkages in dextran. It has many industrial and clinical applications such as food processing, sugar modification, and medicine preparation. Dextranase is widely used to produce alternated sugar beet and isomaltooligosaccharides (IMOs), a prebiotic functional food.PMID 17875335 The low molecular weight dextran obtained from dextranase serves as a synthetic blood volume expander. Dextranase can be coupled to antibodies for the detection of tumor cells.PMID 17875335 It prevents the occurrence of dental plaques by depolymerizing microbial dextran deposits in teeth. Hence, it is used in dental care products.
Preparation Note
A fungal dextranase produced by submerged fermentation of Chaetomium erraticum.
Analysis Note
Stable in the pH range of 3-7 and at temperatures up to approx. 70 °C. For most applications, the preferred conditions are pH 5-6 and a temperature of 50-60 °C.
Other Notes
View more information on enzymes for complex carbohydrate analysis at www.sigma-aldrich.com/enzymeexplorer
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This Item | |||
|---|---|---|---|
| description - | description lyophilized powder, 100-250 units/mg protein | description lyophilized powder, 10-25 units/mg solid | description lyophilized powder, 400-800 units/mg protein |
| form solution | form lyophilized powder | form lyophilized powder | form lyophilized powder |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| Quality Level 300 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Storage Class
10 - Combustible liquids
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