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D5220

Doxorubicin Ready-Made

2mg/ml, Suitable for cell culture

Synonym(s):

Adriamycin, DOX, Hydroxydaunorubicin hydrochloride

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About This Item

NACRES:
NA.76
UNSPSC Code:
12352200
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Quality Level

form

liquid

mol wt

579.98 Da

packaging

pkg of 1 mL

concentration

2 mg/mL

shipped in

dry ice

storage temp.

-10 to -25°C

Biochem/physiol Actions

Doxorubicin is an antitumor antibiotic that acts by inhibiting DNA topoisomerase II. It intercalates with DNA and induces apoptosis by blocking replication.

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1 of 1

This Item
D1515PHR1789D2975000
Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

-

form

liquid

form

powder

form

powder

form

-

storage temp.

-10 to -25°C

storage temp.

2-8°C

storage temp.

-10 to -25°C

storage temp.

-

concentration

2 mg/mL

concentration

-

concentration

-

concentration

-

shipped in

dry ice

shipped in

-

shipped in

-

shipped in

-

packaging

pkg of 1 mL

packaging

-

packaging

pkg of 200 mg

packaging

-


Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Global Trade Item Number

SKUGTIN
D5220-1ML04065266040067

Questions

1–4 of 4 Questions  
  1. What is the molecular formula of the doxorubicin HCl used in this solution?

    1 answer
    1. The Doxorubicin HCl used to prepare this product has a molecular formula of C27H29NO11 · HCl. See product D1515 at the link below for additional details:
      https://www.sigmaaldrich.com/product/sigma/d1515

      Helpful?

  2. la solution de "doxorubicin ready-made" (ref D5220) est diluée dans un buffer: quelle est sa composition ? (sels de phosphates ? ou autre)

    1 answer
    1. This readymade solution contains doxorubicin hydrochloride at a concentration of 2 mg/mL in DMSO. Further information is available under "More Documents" or at this link: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/281/732/d5220pis-rev0922-ms.pdf.

      Helpful?

  3. When this substance is diluted and stored at -10°C to -25°C, what is the recommended storage duration?

    1 answer
    1. This product is stable for at least 2 years in the undiluted state. Stability studies have not been performed on the material when diluted in aqueous solutions. Please see the link below to review a publication that may be helpful.
      https://pubmed.ncbi.nlm.nih.gov/517541/

      Helpful?

  4. What this product is dissolved in? Is it dissolved in water ?

    1 answer
    1. This Ready-Made solution contains doxorubicin hydrochloride at a concentration of 2 mg/mL in DMSO. This solution may be diluted further with buffer or medium.

      Helpful?

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