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E1523

Anti-ERK5 (big-MAPK, BMK1) antibody produced in rabbit

Name: Anti-ERK5 (big-MAPK, BMK1) antibody produced in rabbit
Brand: SIGMA

IgG fraction of antiserum, buffered aqueous solution

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關於此項目

UNSPSC Code:

12352203

NACRES:

NA.44

MDL number:

MFCD01633332

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ARR, WB

Citations:

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屬性

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 97 kDa

species reactivity

mouse, human

technique(s)

microarray: suitable, western blot: 1:8,000 using NIH 3T3 mouse fibroblasts cell extract

UniProt accession no.

Q13164

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MAPK7(5598)
mouse ... Mapk7(23939)

描述

General description

Extracellular signal-regulated kinase 5 (ERK5), also referred to as big-MAP kinase 1 (BMK1), is a protein that belongs to mitogen-activated protein kinases family and is expressed mainly in skeletal muscle, kidney, heart and placenta. ERK5 contains a distinct 400-amino acid C-terminal and loop-12 domain, which includes two proline-rich regions.

Immunogen

synthetic peptide corresponding to amino acids 789-802 of human ERK5.

Application

Anti-ERK5 (big-MAPK, BMK1) an0tibody produced in rabbit has been used in immunoblotting.

Biochem/physiol Actions

Extracellular signal-regulated kinase 5 (ERK5) has a critical role in different cellular processes like differentiation, proliferation and survival. Anti-ERK5 (big-MAPK, BMK1) antibody can be used to study the differential tissue expression and intracellular localization of the MAP Kinase isoform in normal and neoplastic tissues.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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本產品	E7153	M5670	M7431
$Anti-ERK5 (big-MAPK, BMK1) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich E1523 Anti-ERK5 (big-MAPK, BMK1) antibody produced in rabbit	Sigma-Aldrich E7153 Anti-phospho-ERK5 (pThr²¹⁸/pTyr²²⁰) antibody produced in rabbit	Sigma-Aldrich M5670 抗 MAP 激酶 (ERK-1，ERK-2) 兔抗	Sigma-Aldrich M7431 Monoclonal Anti-MAP Kinase 2 (ERK-2) antibody produced in mouse
description IgG fraction of antiserum, buffered aqueous solution	description affinity isolated antibody, buffered aqueous glycerol solution	description whole antiserum	description clone 1B3B9, purified immunoglobulin, buffered aqueous solution
antibody form IgG fraction of antiserum	antibody form affinity isolated antibody	antibody form whole antiserum	antibody form purified immunoglobulin
biological source rabbit	biological source rabbit	biological source rabbit	biological source mouse
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
form buffered aqueous solution	form buffered aqueous glycerol solution	form -	form buffered aqueous solution
mol wt antigen 97 kDa	mol wt -	mol wt antigen ERK-2 42 kDa, antigen, ERK-1 44 kDa	mol wt antigen 42 kDa

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存儲類別/等級

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c