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F3254

Fibrinopeptide A human

≥96% (HPLC)

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Fórmula empírica (notación de Hill):
C63H97N19O26
Número CAS:
25422-31-5
Peso molecular:
1536.56
NACRES:
NA.77
PubChem Substance ID:
24894837
UNSPSC Code:
12352202
MDL number:
MFCD00076437
Form:
powder
Assay:
≥96% (HPLC)
Biological source:
human

biological source

human

Quality Segment

200

assay

≥96% (HPLC)

form

powder

technique(s)

ELISA: suitable, mass spectrometry (MS): suitable

UniProt accession no.

P02671

storage temp.

−20°C

SMILES string

CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CCC(O)=O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(O)=O)NC(=O)C(C)N)C(=O)NC(C)C(=O)NC(CCC(O)=O)C(=O)NCC(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(CCCNC(N)=N)C(O)=O

InChI

1S/C63H97N19O26/c1-29(2)19-37(57(102)73-32(6)53(98)76-35(15-17-48(91)92)55(100)70-24-43(85)68-23-42(84)69-25-46(88)82-51(30(3)4)61(106)77-36(62(107)108)13-10-18-67-63(65)66)79-58(103)38(20-33-11-8-7-9-12-33)80-59(104)39(21-49(93)94)75-45(87)27-71-54(99)34(14-16-47(89)90)74-44(86)26-72-56(101)41(28-83)81-60(105)40(22-50(95)96)78-52(97)31(5)64/h7-9,11-12,29-32,34-41,51,83H,10,13-28,64H2,1-6H3,(H,68,85)(H,69,84)(H,70,100)(H,71,99)(H,72,101)(H,73,102)(H,74,86)(H,75,87)(H,76,98)(H,77,106)(H,78,97)(H,79,103)(H,80,104)(H,81,105)(H,82,88)(H,89,90)(H,91,92)(H,93,94)(H,95,96)(H,107,108)(H4,65,66,67)

InChI key

JWICNZAGYSIBAR-UHFFFAOYSA-N

Gene Information

human ... FGA(2243)

General description

Fibrinopeptide A (FPA) is produced from the N-terminal Aα region of fibrinogen protein, on cleavage by thrombin. It is composed of 16 amino acids.[1]

Application

Fibrinopeptide A human has been used for protein control experiments performed during sandwich ELISA microarray assay to distinguish between plasma and serum fibrinogen samples. It has also been used in a peptide mixture along with BSA (bovine serum albumin) to ascertain the relation between fragmentation voltage and peptide ion drift time for IMS-MS (ion mobility spectrometry coupled with mass spectrometry).[2][3]

Biochem/physiol Actions

Fibrinogen plays essential roles in coagulation of blood, wound healing, platelet aggregation and has roles in various other physiological processes.[4] Increase in the levels of fibrinopeptide A (FPA) is found in multiple disorders such as coronary artery disease, disseminated intravascular coagulation, arterial thrombosis, deep venous thrombosis and cancers.[5]

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Este artículo
F5386MSST0029MSST0013
Fibrinopeptide A human ≥96% (HPLC)

Sigma-Aldrich

F3254

Fibrinopeptide A human

Fibrin from human plasma insoluble powder

Sigma-Aldrich

F5386

Fibrin from human plasma

SILu™Prot APOA2 Apolipoprotein A-II human recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C and 15N-labeled

Sigma-Aldrich

MSST0029

SILu™Prot APOA2 Apolipoprotein A-II human

SILu™Prot AMBP Alpha-1 Microglycoprotein human recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C and 15N-labeled

Sigma-Aldrich

MSST0013

SILu™Prot AMBP Alpha-1 Microglycoprotein human

technique(s)

ELISA: suitable, mass spectrometry (MS): suitable

technique(s)

indirect ELISA: suitable

technique(s)

mass spectrometry (MS): suitable

technique(s)

mass spectrometry (MS): suitable

biological source

human

biological source

human plasma

biological source

human

biological source

human

assay

≥96% (HPLC)

assay

-

assay

≥98% (SDS-PAGE)

assay

≥98% (SDS-PAGE)

form

powder

form

powder

form

lyophilized powder

form

lyophilized powder

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

storage temp.

−20°C

Gene Information

human ... FGA(2243)

Gene Information

human ... FGA(2243), FGB(2244), FGG(2266)

Gene Information

human ... APOA2(336)

Gene Information

human ... AMBP(259)

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Lot/Batch Number

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