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M217

Monoclonal Anti-Nicotinic Acetylcholine Receptor (α₁, α₃, α₅ Subunits) antibody produced in rat

Name: Monoclonal Anti-Nicotinic Acetylcholine Receptor (α1, α3, α5 Subunits) antibody produced in rat
Brand: SIGMA
Price: 1090 EUR

clone mAb 35, purified immunoglobulin, buffered aqueous solution

Synonym(e):

Anti-ACHR

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Ihnen/SKU	Verfügbarkeit	Preis
100 μL	Warenkorb auf Verfügbarkeit prüfen	€ 1.090,00

Über diesen Artikel

UNSPSC Code:

12352203

NACRES:

NA.43

MDL number:

MFCD00677279

Conjugate:

unconjugated

Clone:

mAb 35, monoclonal

Application:

IHC (f)

Citations:

€ 1.090,00

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Technischer Dienst

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Unterstützung erhalten

Eigenschaften

biological source

rat

Quality Segment

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

mAb 35, monoclonal

form

buffered aqueous solution

species reactivity

human, chicken, eel

should not react with

Xenopus

technique(s)

immunohistochemistry (frozen sections): 1:3,000

isotype

IgG1

UniProt accession no.

CHRNA1

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CHRNA1(1134), CHRNA3(1136), CHRNA5(1138)

Beschreibung

Immunogen

nicotinic acetylcholine receptor from the electric eel Electrophorus.

Biochem/physiol Actions

Binds to the main immunogenic region on the extracellular surface of the α₁ subunit of muscle AChR′s and to homologous regions on α₃ and α₅ subunits of neuronal AChR′s. The epitope is located on the extracellular surface of the α₁ subunit of the muscle nicotinic acetylcholine receptor. The antibody binds to denatured chick α₅ AChR, but does not bind well to denatured α₃, α₄, α₇, α_8, and β₂. It may also bind β₃ due to homology of main immunogenic region. May be used to localize and detect the α₁, α₃ and α₅ subunits of the nicotinic acetylcholine receptor (AChR).

Physical form

Solution in 20 mM Na₃PO₄, pH 7.2, containing 150 mM NaCl and 0.05 % sodium azide.

Legal Information

Sold with permission of the Salk Institute

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Dieser Artikel	AV34910	AV34909	WH0001138M1
Sigma-Aldrich M217 Monoclonal Anti-Nicotinic Acetylcholine Receptor (α₁, α₃, α₅ Subunits) antibody produced in rat	Sigma-Aldrich AV34910 Anti-CHRNA1 (AB2) antibody produced in rabbit	Sigma-Aldrich AV34909 Anti-CHRNA1 (AB1) antibody produced in rabbit	Sigma-Aldrich WH0001138M1 Monoclonal Anti-CHRNA5 antibody produced in mouse
species reactivity human, chicken, eel	species reactivity human, guinea pig, bovine, horse, mouse, dog, rat, rabbit	species reactivity human	species reactivity human
antibody form purified immunoglobulin	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form purified immunoglobulin
biological source rat	biological source rabbit	biological source rabbit	biological source mouse
clone mAb 35, monoclonal	clone polyclonal	clone polyclonal	clone 7D3, monoclonal
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
Gene Information human ... CHRNA1(1134), CHRNA3(1136), CHRNA5(1138)	Gene Information human ... CHRNA1(1134)	Gene Information human ... CHRNA1(1134)	Gene Information human ... CHRNA5(1138)

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Lagerklasse

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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