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S3147

5-Sulfosalicylic acid dihydrate

suitable for electrophoresis, ≥99%

Synonym(s):

2-Hydroxy-5-sulfobenzoic acid

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About This Item

Linear Formula:
HO3SC6H3-2-(OH)CO2H·2H2O
CAS Number:
Molecular Weight:
254.21
UNSPSC Code:
41105319
NACRES:
NB.22
PubChem Substance ID:
EC Number:
202-555-6
Beilstein/REAXYS Number:
650741
MDL number:


Quality Segment

assay

≥99%

form

powder or crystals

technique(s)

electrophoresis: suitable

impurities

≤0.02% Insoluble matter, ≤0.05% Salicylic Acid

mp

105-110 °C (lit.)

solubility

water: soluble 100 mg/mL, clear, colorless

anion traces

chloride (Cl-): ≤0.001%, sulfate (SO42-): ≤0.035%

cation traces

Fe: ≤0.001%, heavy metals (as Pb): ≤0.002%

SMILES string

[H]O[H].[H]O[H].OC(=O)c1cc(ccc1O)S(O)(=O)=O

InChI

1S/C7H6O6S.2H2O/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10;;/h1-3,8H,(H,9,10)(H,11,12,13);2*1H2

InChI key

BHDKTFQBRFWJKR-UHFFFAOYSA-N

General description

5-Sulfosalicylic acid is a strong acid capable of protonating water. It forms a new theophylline complex, which was investigated by X-ray photoelectron spectroscopy (XPS).[1] It forms 1:1 proton-transfer compounds with the ortho-substituted monocyclic heteroaromatic Lewis bases. Their crystal structures have been studied.

Application

5-Sulfosalicylic acid dihydrate may be employed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma by HPLC.[2] It may be used in the preparation of poly[[tris(di-2-pyridylamine)tris([μ]-5-sulfonatosalicylato)tricopper(II)] trihydrate].
5-Sulfosalicylic acid (3.5%) in 12% trichloroacetic acid is commonly used as a fixing solution for proteins in agarose and polyacrylamide gels.

Analysis Note

Tested for use in fixing solutions for PAGE, SDS-PAGE and IEF.

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This Item
861952470068.00691
description

suitable for electrophoresis, ≥99%

description

purum p.a., ≥98.0% (T)

description

ACS reagent, ≥99%

description

for synthesis

technique(s)

electrophoresis: suitable

technique(s)

-

technique(s)

-

technique(s)

-

assay

≥99%

assay

≥98.0% (T)

assay

≥99%, 99.0-101.0% (ACS specification)

assay

≥99.0% (acidimetric)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder or crystals

form

solid

form

solid

form

crystals

solubility

water: soluble 100 mg/mL, clear, colorless

solubility

water: soluble 127.1 g/L at 20 °C

solubility

water: soluble 127.1 g/L at 20 °C

solubility

soluble 987 g/L

anion traces

chloride (Cl-): ≤0.001%, sulfate (SO42-): ≤0.035%

anion traces

chloride (Cl-): ≤50 mg/kg

anion traces

chloride (Cl-): ≤0.001%, sulfate (SO42-): ≤0.02%

anion traces

-


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pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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