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S7635

Sulforhodamine 101

Dye content ~95 %, Powder

Synonym(s):

SR101; 2-(3-oxa-23-aza-9-azoniaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]octacosa-1(27),2(17),4,9(28),13,15,18-heptaen-16-yl)-5-sulfobenzenesulfonate

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$557.00

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About This Item

Empirical Formula (Hill Notation):
C31H30N2O7S2
CAS Number:
60311-02-6
Molecular Weight:
606.71
NACRES:
NA.47
PubChem Substance ID:
24899749
UNSPSC Code:
12171500
EC Number:
262-159-4
MDL number:
MFCD00012407
Beilstein/REAXYS Number:
3582548

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Product Name

Sulforhodamine 101, Dye content ~95 %

InChI

1S/C31H30N2O7S2/c34-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-32-13-3-7-22(28(18)32)30(24)40-31-23-8-4-14-33-12-2-6-19(29(23)33)16-25(27)31/h9-10,15-17H,1-8,11-14H2,(H-,34,35,36,37,38,39)

InChI key

COIVODZMVVUETJ-UHFFFAOYSA-N

SMILES string

OS(=O)(=O)c1ccc(C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)c(c1)S([O-])(=O)=O

form

powder

composition

Dye content, ~95%

technique(s)

microbe id | staining: suitable

color

black, dark green to brown

solubility

methanol: 1 mg/mL

ε (extinction coefficient)

≥105000 at 573-579 nm in ethanol

fluorescence

λex 586 nm; λem 605 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

100

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1 of 4

This Item
230162S9012S1402
Sulforhodamine 101 Dye content ~95 %

Sigma-Aldrich

S7635

Sulforhodamine 101

Sulforhodamine B Dye content 75 %

Sigma-Aldrich

230162

Sulforhodamine B

Sulforhodamine B sodium salt Technical grade

Sigma-Aldrich

S9012

Sulforhodamine B sodium salt

Sulforhodamine B sodium salt powder, BioReagent, suitable for cell culture

Sigma-Aldrich

S1402

Sulforhodamine B sodium salt

technique(s)

microbe id | staining: suitable

technique(s)

microbe id | staining: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

color

black, dark green to brown

color

brown to very dark brown, green to very dark green

color

-

color

-

fluorescence

λex 586 nm; λem 605 nm in H2O

fluorescence

-

fluorescence

-

fluorescence

λex 565 nm; λem 586 nm in H2O

solubility

methanol: 1 mg/mL

solubility

methanol: 1 mg/mL

solubility

-

solubility

methanol: 1 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

form

powder

form

powder

form

powder

form

powder

General description

Sulforhodamine 101 is a red fluorescent dye. It is water-soluble, amphoteric rhodamine.[1]

Application

Sulforhodamine 101 has been used:
  • to label astrocytes[2]
  • in quantitative polymerase chain reaction (PCR)[3]
  • to determine the degree of disintegration in tissue sample[4]

Biochem/physiol Actions

Sulforhodamine 101 can be specifically used as a marker of astroglia in the neocortex.[1] It is commonly used for brain imaging.[5] Studies suggest that sulforhodamine 101 may be used as an epileptogenic agent.[6]

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SHBR5977
SHBR9644
SHBR7199
SHBR0266
SHBP7695

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Stimulus-Evoked Calcium Transients in Somatosensory Cortex Are Temporarily Inhibited by a Nearby Microhemorrhage
Flor A
PLoS ONE (2013)
Single-cell genetic analysis of ductal carcinoma in situ and invasive breast cancer reveals enormous tumor heterogeneity yet conserved genomic imbalances and gain of MYC during progression
Heselmeyer HK, et al.
The American Journal of Pathology, 181(5), 1807-1822 (2012)
Takashi Yoshida et al.
Nature communications, 11(1), 872-872 (2020-02-15)
Natural scenes sparsely activate neurons in the primary visual cortex (V1). However, how sparsely active neurons reliably represent complex natural images and how the information is optimally decoded from these representations have not been revealed. Using two-photon calcium imaging, we
Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo
Nimmerjahn A, et al.
Nature Methods, 1(1), 31-31 (2004)
Jumpei Ukita et al.
Scientific reports, 9(1), 3791-3791 (2019-03-09)
A comprehensive understanding of the stimulus-response properties of individual neurons is necessary to crack the neural code of sensory cortices. However, a barrier to achieving this goal is the difficulty of analysing the nonlinearity of neuronal responses. Here, by incorporating
View All Related Papers

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