Key Documents

Monoclonal Anti-Siah2 antibody produced in mouse

Name: Monoclonal Anti-Siah2 antibody produced in mouse
Brand: SIGMA
Price: 620.5 USD
Availability: InStock

clone Siah2-369, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-Seven in Absentia Homolog

Select a Size

Change View

Size/SKU	Availability	Price
200 μL	Available to ship TODAYfromMILWAUKEE	$730.00 $620.50

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD08705601

Conjugate:

unconjugated

Clone:

Siah2-369, monoclonal

Application:

ARR, ELISA (i), ICC, WB

Citations:

$620.50

List Price$730.00Save 15%

Web-Only Promotion

Available to ship TODAYDetails

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

Siah2-369, monoclonal

form

buffered aqueous solution

mol wt

antigen ~37 kDa

species reactivity

monkey, hamster, bovine, mouse, human, canine

technique(s)

immunocytochemistry: suitable, indirect ELISA: suitable, microarray: suitable, western blot: 2-4 μg/mL using total cell extract of HeLa cells

isotype

IgG1

UniProt accession no.

O43255

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SIAH2(6478)
mouse ... Siah2(20439)

Description

General description

Monoclonal Anti-Siah2 (mouse IgG1 isotype) is derived from the hybridoma Siah2-369 produced by the fusion of mouse myeloma cells (NS1 cell) and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to amino acids 2-17 of human Siah2, conjugated to KLH. Seven in absentia homologue (Siah) is encoded by the gene mapped to human chromosome 3q25.1. Three different Siah genes exist in mice, Siah1a, Siah1b, and Siah2, while humans have only two genes, Siah1and Siah2.

Immunogen

synthetic peptide corresponding to amino acids 2-17 of human Siah2, conjugated to KLH.

Application

Monoclonal Anti-Siah2 antibody produced in mouse can be used in enzyme linked immunoassay (ELISA) and immunocytochemistry. It has also been used in immunohistochemistry and immunoblotting.

Biochem/physiol Actions

Seven in absentia homologue (Siah) plays a role in the regulation of key proteins in the immune system such as TNF receptor associated factors (TRAF), vav guanine nucleotide exchange factor 1 (Vav1), and oct-binding factor 1 (OBF-1). Siah2 is important for the regulation of the PHD enzymes (prolylhydroxylases) that are responsible for the prolyhydroxylation of HIFα protein under hypoxia conditions.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	SAB4502777	AV38212	P8996
Sigma-Aldrich S7945 Monoclonal Anti-Siah2 antibody produced in mouse	Sigma-Aldrich SAB4502777 Anti-SIAH1 antibody produced in rabbit	$Anti-SIAH1 (AB2) antibody produced in rabbit IgG fraction of antiserum$ Sigma-Aldrich AV38212 Anti-SIAH1 (AB2) antibody produced in rabbit	Sigma-Aldrich P8996 Monoclonal Anti-PINCH-1 antibody produced in mouse
description clone Siah2-369, purified immunoglobulin, buffered aqueous solution	description affinity isolated antibody	description IgG fraction of antiserum	description clone PINCH-C58, purified immunoglobulin, buffered aqueous solution
biological source mouse	biological source rabbit	biological source rabbit	biological source mouse
clone Siah2-369, monoclonal	clone polyclonal	clone polyclonal	clone PINCH-C58, monoclonal
Gene Information human ... SIAH2(6478) mouse ... Siah2(20439)	Gene Information human ... SIAH1(6477)	Gene Information human ... SIAH1(6477)	Gene Information human ... LIMS1(3987) mouse ... Lims1(110829) rat ... Gcc2(309798)
antibody form purified immunoglobulin	antibody form affinity isolated antibody	antibody form IgG fraction of antiserum	antibody form purified immunoglobulin
species reactivity monkey, hamster, bovine, mouse, human, canine	species reactivity human, rat, mouse	species reactivity guinea pig, mouse, rat, bovine, rabbit, human, horse, dog	species reactivity hamster, bovine, mouse, monkey, canine, human, rat
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated

Still not finding the right product?

Explore all of our products under Monoclonal Anti-Siah2 antibody produced in mouse

— or —

Try our Product Selector Tool to narrow your options

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.