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S8939

SGK1 (δ1-60, S422D), active human

recombinant, expressed in baculovirus infected Sf9 cells (truncated human sequence (a.a. 1-60 deleted, S422D mutation)-histidine-tagged), buffered aqueous solution

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2 μg
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$1,040.00

About This Item

UNSPSC Code:
51111800
NACRES:
NA.32
MDL number:
Recombinant:
expressed in baculovirus infected Sf9 cells (truncated human sequence (a.a. 1-60 deleted, S422D mutation)-histidine-tagged)

$1,040.00


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recombinant

expressed in baculovirus infected Sf9 cells (truncated human sequence (a.a. 1-60 deleted, S422D mutation)-histidine-tagged)

Quality Segment

form

buffered aqueous solution

mol wt

~48 kDa by SDS-PAGE

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... SGK1(6446)

General description

The serum- and glucocorticoid-regulated kinase (SGK1) is a member of the AGC kinase family and the gene encoding it is localized on human chromosome 6q23.

Biochem/physiol Actions

The serum- and glucocorticoid-regulated kinase (SGK1) has a role in the hormonal regulation of ion channels and pumps. It has been associated with cancers. The protein modulates nitric oxide production by activating NO synthase. SGK1 protects cells from apoptosis and oxidative stress.
Kinase assays.

Physical form

Solution in 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 0.15 M NaCl, 0.03% Brij® L23, 1 mM benzamidine, 0.2 mM PMSF. and 270 mM sucrose.

Other Notes

One unit of SGK1 = 1 nmol phosphate incorporated into crosstide substrate peptide in one minute.

Legal Information

Brij is a registered trademark of Croda International PLC

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This Item
S7073SAB5700669S6948
Gene Information

human ... SGK1(6446)

Gene Information

human ... SGK1(6446)

Gene Information

human ... SGK1(6446)

Gene Information

human ... SGK2(10110)

form

buffered aqueous solution

form

buffered aqueous glycerol solution

form

buffered aqueous solution

form

buffered aqueous glycerol solution

recombinant

expressed in baculovirus infected Sf9 cells (truncated human sequence (a.a. 1-60 deleted, S422D mutation)-histidine-tagged)

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

-

recombinant

expressed in baculovirus infected Sf9 cells

mol wt

~48 kDa by SDS-PAGE

mol wt

~73 kDa

mol wt

47, 48, 50, 52, 59

mol wt

~71 kDa

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−20°C

storage temp.

−70°C

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

shipped in

dry ice


Storage Class

10 - Combustible liquids



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