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MilliporeSigma

SBR00102

Abrocitinib

≥95%

Synonym(s):

N-[cis-3-(Methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-1-propanesulfonamide (ACI), N-[cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]propane-1-sulfonamide

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About This Item

Empirical Formula (Hill Notation):
C14H21N5O2S
CAS Number:
Molecular Weight:
323.41
UNSPSC Code:
51101500
NACRES:
NA.21
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Quality Segment

assay

≥95%

application(s)

advanced drug delivery

mode of action

enzyme | inhibits

storage temp.

2-8°C

SMILES string

O=S(=O)(NC1CC(N(C=2N=CN=C3NC=CC32)C)C1)CCC

InChI

InChI=1/C14H21N5O2S/c1-3-6-22(20,21)18-10-7-11(8-10)19(2)14-12-4-5-15-13(12)16-9-17-14/h4-5,9-11,18H,3,6-8H2,1-2H3,(H,15,16,17)/t10-,11+

InChI key

IUEWXNHSKRWHDY-PHIMTYICNA-N

General description

Abrocitinib is an antibiotic which is a Janus Kinase (JAK) inhibitor.

Biochem/physiol Actions

Mode of Action:

Abrocitinib blocks activity of certain enzymes called JAKs, like JAK1. JAKs are involved in transmitting signals from cytokine receptors to the nucleus of cells, thereby regulating various cellular processes including immune responses.

Antimicrobial Spectrum:

Abrocitinib does not have a direct antimicrobial effect.

Features and Benefits

High quality antibiotic suitable for mulitple research applications Commonly used in Cell Biology and Biochemical applications


Hazard Codes

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Pictograms

Exclamation mark

Signal Word

Warning

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

No data available

Flash Point (°C)

No data available



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