This product is supplied as a powder, not in tablet form. This material is intended for research use only and is not suitable for human or veterinary use.
SML3275
Vamorolone
≥95% (HPLC)
Synonym(s):
(16α)-17,21-Dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione, (16α)-17,21-Dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione;, VBP 15, VBP15
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | $140.00 |
25 mg | Please contact Customer Service for Availability | $559.00 |
About This Item
Empirical Formula (Hill Notation):
C22H28O4
CAS Number:
Molecular Weight:
356.46
UNSPSC Code:
12352200
NACRES:
NA.84
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
$140.00
Please contact Customer Service for Availability
Quality Segment
assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
O[C@]1([C@@]2([C@H]([C@@H]3CCC4=CC(=O)C=C[C@@]4(C3=CC2)C)C[C@H]1C)C)C(=O)CO
InChI
1S/C22H28O4/c1-13-10-18-16-5-4-14-11-15(24)6-8-20(14,2)17(16)7-9-21(18,3)22(13,26)19(25)12-23/h6-8,11,13,16,18,23,26H,4-5,9-10,12H2,1-3H3/t13-,16-,18+,20+,21+,22+/m1/s1
InChI key
ZYTXTXAMMDTYDQ-DGEXFFLYSA-N
Biochem/physiol Actions
Orally available dissociative steroid with anti-inflammatory efficacy
Vamorolone, a synthetic steroid, is an orally available dissociative steroid with anti-inflammatory efficacy. It is a partial agonist of the glucocorticoid receptor (NR3C1) that appear to be safe and well tolerated. Also, vamorolone is a potent antagonist of the mineralocorticoid receptor (NR3C2). It is under development for children with Duchenne muscular dystrophy.
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This Item | |||
|---|---|---|---|
| description ≥95% (HPLC) | description certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland | description British Pharmacopoeia (BP) Reference Standard | description European Pharmacopoeia (EP) Reference Standard |
| assay ≥95% (HPLC) | assay - | assay - | assay - |
| form powder | form - | form powder | form - |
| Quality Level 100 | Quality Level 300 | Quality Level - | Quality Level - |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - |
| solubility DMSO: 2 mg/mL, clear | solubility - | solubility - | solubility - |
| color white to beige | color - | color - | color - |
Hazard Codes
Signal Word
Warning
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Sens. 1
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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