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Merck

SML3392

BC-11 hydrobromide

≥98% (HPLC)

Synonym(s):

Carbamimidothioic acid (4-boronophenyl)methyl ester hydrobromide

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About This Item

Empirical Formula (Hill Notation):
C8H11BN2O2S·HBr
CAS Number:
Molecular Weight:
290.97
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear (warmed)

storage temp.

−20°C

SMILES string

B(O)(O)c1ccc(cc1)CS\C(=N/[H])\N.Br

InChI

1S/C8H11BN2O2S.BrH/c10-8(11)14-5-6-1-3-7(4-2-6)9(12)13;/h1-4,12-13H,5H2,(H3,10,11);1H

InChI key

PAFZAMOVHIRQOD-UHFFFAOYSA-N

Biochem/physiol Actions

BC-11 is a potent and selective inhibitor of urokinase (urokinase-plasminogen activator, uPA). BC-11 inhibits clot lysis with no effect on clot formation. BC-11 exhibits anti-fibrotic activity and improves wound healing and scar quality after topical administration in mice.
potent and selective inhibitor of urokinase (urokinase-plasminogen activator, uPA)


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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