SML3431
JBSNF-000088
≥98% (HPLC)
Synonym(s):
6-Methoxy-3-pyridinecarboxamide, 6-Methoxyniacinamide, 6-Methoxynicotinamide, NSC 70628
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About This Item
Empirical Formula (Hill Notation):
C7H8N2O2
CAS Number:
Molecular Weight:
152.15
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
NC(=O)c1cnc(cc1)OC
InChI
1S/C7H8N2O2/c1-11-6-3-2-5(4-9-6)7(8)10/h2-4H,1H3,(H2,8,10)
InChI key
KXDSMFBEVSJYRF-UHFFFAOYSA-N
Biochem/physiol Actions
JBSNF-000088 is a cell penetrant, potent and selective inhibitor of Nicotinamide N-methyltransferase (NNMT) that reduces 1-methyl-nicotinamide (MNA) and improved glucose control in mice models of metabolic disease. JBSNF-000088 potently inhibits growth of PFA ependymoma cells.
cell penetrant, potent and selective inhibitor of Nicotinamide N-methyltransferase (NNMT)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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