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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | $157.00 |
25 mg | Please contact Customer Service for Availability | $631.00 |
About This Item
Empirical Formula (Hill Notation):
C11H9F3N4O2S
CAS Number:
Molecular Weight:
318.27
UNSPSC Code:
12352200
NACRES:
NA.21
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(NC1=CC(F)=NC=C1CO)NC2=CC(C(F)F)=NS2
InChI
1S/C11H9F3N4O2S/c12-8-1-6(5(4-19)3-15-8)16-11(20)17-9-2-7(10(13)14)18-21-9/h1-3,10,19H,4H2,(H2,15,16,17,20)
InChI key
CKYCAIAVJIFWPE-UHFFFAOYSA-N
Biochem/physiol Actions
NVP-RXI570 is an orally active, potent, and selective allosteric dual inhibitor of BRM ((SMARCA2) and BRG1 (SMARCA4) that that downregulates BRM-dependent gene expression. NVP-RXI570 exhibits antiproliferative activity in a BRG1 mutant-lung-tumor xenograft model.
Orally active, potent, and selective allosteric dual inhibitor of BRM ((SMARCA2) and BRG1 (SMARCA4)
1 of 1
This Item | |||
|---|---|---|---|
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 20 mg/mL, clear | solubility DMSO: 2 mg/mL, clear |
| color white to beige | color white to beige | color white to beige | color white to beige |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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