SML3581
NVP-ACQ090
≥98% (HPLC)
Synonym(s):
1-[[(4S,4aS,8aR)-Decahydro-2-[(2S)-3-(6-methoxy-3-pyridinyl)-2-methylpropyl]-4-isoquinolinyl]carbonyl]-4-(3,4-difluorophenyl)-piperazine, ACQ 090, ACQ-090, ACQ090, [(4S,4aS,8aR)-Decahydro-2-[(2S)-3-(6-methoxy-3-pyridinyl)-2-methylpropyl]-4-isoquinolinyl][4-(3,4-difluorophenyl)-1-piperazinyl]methanone, [4-(3,4-Difluoro-phenyl)-piperazine-1-yl]-{(4S,4aS,8aR)-2[(S)-3-(6-methoxy-pyridin-3-yl)-2-methyl-propyl]-decahydroisoquinoline-4-yl}-methanone
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About This Item
Empirical Formula (Hill Notation):
C30H40F2N4O2
CAS Number:
Molecular Weight:
526.66
NACRES:
NA.77
UNSPSC Code:
51111800
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
NVP-ACQ090 is a non-peptidic, potent and subtype-selective somatostatin (SRIF; somatotropin release-inhibiting factor) receptor (SST3; SSTR3) antagonist (hSST3 pKD = 8.15, hSSTR1/2/4/5 pKD = 5.69/5.34/5.83/5.95). NVP-ACQ090 blocks hSST3 phosphorylation induced by somatostatin-14 (SS-14) in cultures and impaires object recognition in wild-type mice in vivo (50 μg/kg i.p.).
Non-peptidic, potent and subtype-selective somatostatin (SRIF; somatotropin release-inhibiting factor) receptor (SST3; SSTR3) antagonist in vitro and in vivo
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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