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SML3877

SRI-32743

≥98% (HPLC)

Synonym(s):

2-(7-Methylimidazo[1,2-a]pyridin-6-yl)-N-(2-phenylbutyl)-4-quinazolinamine

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About This Item

Empirical Formula (Hill Notation):
C26H25N5
CAS Number:
1940118-42-2
Molecular Weight:
407.51
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Warmed)

storage temp.

2-8°C

Biochem/physiol Actions

Allosteric modulator of monoamine transporters that acts as partial antagonists of dopamine uptake.

SRI-32743 is an allosteric modulator of monoamine transporters that acts as partial antagonists of dopamine uptake. SRI-32743 attenuates Tat (the HIV regulatory protein transactivator of transcription) induced inhibition of DAT-mediated dopamine uptake. Also, it alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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