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SML3899

L-371,257

≥98% (HPLC)

Synonym(s):

1-[4-[(1-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)-piperidine, L 371257

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About This Item

Empirical Formula (Hill Notation):
C28H33N3O6
CAS Number:
162042-44-6
Molecular Weight:
507.58
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
MFCD00944944
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

Highly potent and selective oxytocin receptor antagonist
L-371,257 is a highly potent and selective antagonist of human oxytocin receptor. L-371,257 potently inhibits oxytocin-induced contractions of the rat uterus in vitro and in vivo. L-371,257 exhibits good oral availability in rats. It exhibits good peripheral selectivity.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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