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MilliporeSigma

SML3927

Alalevonadifloxacin hydrochloride

≥98% (HPLC)

Synonym(s):

L-Alanine 1-[(5S)-2-carboxy-9-fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizin-8-yl]-4-piperidinyl ester hydrochloride, WCK 2349 hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C22H26FN3O5·HCl
CAS Number:
Molecular Weight:
467.92
NACRES:
NA.77
UNSPSC Code:
51111800
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

Orally available L-alanine ester prodrug of Levonadifloxacin that is affective against Gram-positive and Gram-negative bacteria.


Alalevonadifloxacin, the L-alanine ester prodrug of levonadifloxacin, is an orally available and potent benzoquinolizine fluoroquinolone antibiotic that is affective against Gram-positive and Gram-negative bacteria, including methicillin- and quinolone-resistant Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, and Moraxella catarrhalis and atypical pathogens. Alalevonadifloxacin targets staphylococcal DNA gyrase, unlike other quinolones, which primarily inhibit DNA topoisomerase IV.

Disclaimer

Hygroscopic


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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