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SML4048

LEI-102

≥95% (HPLC)

Synonym(s):

1-[[4-[5-Fluoro-6-[[(tetrahydro-2H-pyran-4-yl)amino]methyl]-2-pyridinyl]phenyl]methyl]-3-(2-methylpropyl)-2,4-imidazolidinedione

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About This Item

Empirical Formula (Hill Notation):
C25H31FN4O3
CAS Number:
1228659-40-2
Molecular Weight:
454.54
NACRES:
NA.21
Assay:
≥95% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥95% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(N1CC(C)C)N(CC2=CC=C(C=C2)C3=CC=C(C(CNC4CCOCC4)=N3)F)CC1=O

Biochem/physiol Actions

Orally available potent and selective cannabinoid CB2 receptor agonist.
LEI-102 is orally available, highly potent and highly selective cannabinoid CB2 receptor agonist. LEI-102 attenuates cisplatin-induced nephrotoxicity in mice. LEI-102 did not generate CB1R-mediated CNS-side effects at doses up to 25mg/kg (p.o.) in mice model.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H315

Hazard Classifications

Acute Tox. 4 Oral - Skin Irrit. 2

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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