SML4087
Spns2 inhibitor 16d
≥98% (HPLC)
Synonym(s):
3-(4-Decylphenyl)-1,2,4-oxadiazole-5-propanamine hydrochloride, SLF1081851
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About This Item
Empirical Formula (Hill Notation):
C21H33N3O·HCl
CAS Number:
Molecular Weight:
379.97
UNSPSC Code:
41106300
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
CCCCCCCCCCC1=CC=C(C=C1)C2=NOC(CCCN)=N2.Cl
InChI
1S/C21H33N3O.ClH/c1-2-3-4-5-6-7-8-9-11-18-13-15-19(16-14-18)21-23-20(25-24-21)12-10-17-22;/h13-16H,2-12,17,22H2,1H3;1H
InChI key
ZJJXKBLUUGLWDW-UHFFFAOYSA-N
Biochem/physiol Actions
Potent and selective inhibitor of Spns2 (spinster homolog 2) sphingosine-1-phosphate (SP1) transporter.
Spns2 inhibitor 16d (SLF1081851) is a potent and selective inhibitor of Spns2 (spinster homolog 2) sphingosine-1-phosphate (SP1) transporter. Spns2 inhibitor 16d (SLF1081851) decreases circulating plasma S1P and lymphocytes in mice and rats. Apparently, it locks Spns2 in the inward-facing state.
Spns2 inhibitor 16d (SLF1081851) is a potent and selective inhibitor of Spns2 (spinster homolog 2) sphingosine-1-phosphate (SP1) transporter. Spns2 inhibitor 16d (SLF1081851) decreases circulating plasma S1P and lymphocytes in mice and rats. Apparently, it locks Spns2 in the inward-facing state.
Disclaimer
Hygroscopic
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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