Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C17H18F2N4O3
CAS Number:
Molecular Weight:
364.35
NACRES:
NA.28
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(NCC1CCOCC1)C2=NNC=C2NC(C3=C(C=CC=C3F)F)=O
Biochem/physiol Actions
Potent and selective glycogen synthase kinase-3 (GSK3⍺/β) inhibitor.
SGC-GSK3-1 is a potent and selective glycogen synthase kinase-3 inhibitor (GSK3⍺/β IC50 = 1/2 nM by cell-free enzymatic assay, 4.6/12 nM by cellular NanoBRET) that protects iPSC-derived motor neurons from ER stress-induced death.
SGC-GSK3-1 is a potent and selective glycogen synthase kinase-3 inhibitor (GSK3⍺/β IC50 = 1/2 nM by cell-free enzymatic assay, 4.6/12 nM by cellular NanoBRET) that protects iPSC-derived motor neurons from ER stress-induced death.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.