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SML4209

BHB-Phe

Name: BHB-Phe
Brand: SIGMA

≥98% (HPLC), powder, BHB secondary metabolite

Synonym(s):

N-[(3R)-3-Hydroxy-1-oxobutyl]-L-Phenylalanine

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About This Item

Empirical Formula (Hill Notation):

C₁₃H₁₇NO₄

CAS Number:

3017120-67-8

Molecular Weight:

251.28

NACRES:

NA.21

Assay:

≥98% (HPLC)

Form:

powder

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Properties

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

C[C@@H](O)CC(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O

Description

General description

BHB-Phe is a β-Hydroxybutyrate (BHB) secondary metabolite present in human and mouse plasma. It is a ketosis-inducible structural and functional congener of lactate-phenylalanine.

Application

BHB-Phe may be used for examining its effects on metabolic pathways during states of ketosis and studying its interactions with the carnosine dipeptidase 2 (CNDP2) enzyme.

Biochem/physiol Actions

BHB-Phe exhibits anti-obesity activities hence reducing food intake and body weight in diet-induced obese (DIO) mice. Apparently BHB-Phe activates hypothalamic and brainstem neurons and suppresses feeding. BHB-Phe issynthesized in the body by catalytic condensation of BHB and Phenylalanine by carnosine dipeptidase 2 (CNDP2).

pictograms

GHS05,GHS07

signalword

Danger

hcodes

H302,H318

pcodes

P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c