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SML4228

20α-Hydroxycholesterol

≥98% (HPLC)

Synonym(s):

(3β)-Cholest-5-ene-3,20-diol, 20α-Hydroxy cholesterol, 20(S)-Hydroxycholesterol

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About This Item

Empirical Formula (Hill Notation):
C27H46O2
CAS Number:
516-72-3
Molecular Weight:
402.65
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

-10 to -25°C

Biochem/physiol Actions

20α-Hydroxycholesterol is a brain penetrant oxysterol present in human breast milk, human placenta and the mammalian CNS, which attenuates white matter injuries in neonatal mice. 20α-Hydroxycholesterol induces oligodendrogenesis through a sonic hedgehog Gli family zinc finger signaling activation mechanism. It increases numbers of mature oligodendrocytes, improves myelination, and rescues motor deficits.

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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