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SML4353

JNJ-9350

≥97% (HPLC)

Synonym(s):

JNJ 9350, JNJ9350, N- (3-(1H-Imidazol-1-yl)propyl)-5, 7-diphenylpyrazolo[1, 5-a]pyrimidine-2-carboxamide

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About This Item

Empirical Formula (Hill Notation):
C25H22N6O
CAS Number:
326923-09-5
Molecular Weight:
422.48
UNSPSC Code:
12352200
Assay:
≥97% (HPLC)
Form:
powder
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Quality Segment

assay

≥97% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

JNJ-9350 is a potent and selective spermine oxidase (SMOX) inhibitor (IC50 = 10 nM/SMOX, 739 nM/PAOX) that exhibits 20-times higher cellular SMOX engagement efficacy than MDL72527 (IC50 = 1.2 µM vs 23.7 µM by celluar thermal shift assay using A549 cells).

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Codes

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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