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About This Item
Empirical Formula (Hill Notation):
C28H19P
CAS Number:
Molecular Weight:
386.42
UNSPSC Code:
12352200
Assay:
≥97% (HPLC)
Form:
powder
Quality Segment
assay
≥97% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
Biochem/physiol Actions
Diphenyl-1-pyrenylphosphine (DPPP) is a non-fluorescent, lipophilic probe specifically designed for quantitative detection of lipid peroxidation within cellular membranes. Upon reaction with lipid hydroperoxides, DPPP undergoes an irreversible and stoichiometric oxidation, transforming into a highly fluorescent oxide, DPPP=O (λex 351 nm, λem 380 nm), enabling precise quantitative analysis. This membrane-selective and low-toxicity probe distinguishes itself from hydrophilic probes, offering minimal perturbation to cellular physiology while specifically targeting membrane oxidation events. DPPP’s key advantage lies in its ability to directly and specifically monitor lipid peroxidation (LPO) occurring in the membrane environment in real-time with high sensitivity, facilitating detection down to femtomole levels of peroxides.
Storage Class
11 - Combustible Solids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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