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About This Item
Empirical Formula (Hill Notation):
C28H25N3O4
CAS Number:
Molecular Weight:
467.52
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated, protect from light
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated, protect from light
color
red to very dark purple
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
TAMRA-Alkyne is a cell-permeable, and photostable bioorthogonal probe for the high-fidelity covalent labeling of azide-functionalized biomolecules. This tool leverages the bright, orange-red fluorescence (λex/λem ~546 nm/579 nm) of an isomerically pure 5-TAMRA core and the specificity of copper-catalyzed click chemistry. It is specifically designed as a compact, fluorescent alkyne for situations where larger, PEGylated probes might introduce steric interference or are otherwise undesirable, offering a minimal steric footprint for probing constrained molecular environments. While TAMRA-alkyne’s hydrophobicity necessitates rigorous protocols to manage non-specific binding, it remains a valuable tool for fixed-cell imaging where a small tag is paramount for achieving high-resolution visualization.
Disclaimer
Hygroscopic, Store with desiccant
Storage Class
11 - Combustible Solids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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