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MilliporeSigma

SML4449

Lentinan

Synonym(s):

Biomoduline, LC 33

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About This Item

Empirical Formula (Hill Notation):
(C42H70O35)n
CAS Number:
UNSPSC Code:
12352200
Form:
powder
Storage condition:
desiccated
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form

powder

Quality Segment

storage condition

desiccated

color

faint beige to brown

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

-10 to -25°C

Biochem/physiol Actions

Lentinan is a β-(1,3)-glucan with β-(1,6) branches, extracted primarily from shiitake mushrooms and used in medicine and dietary supplements. It exhibits potential antitumor, anti-inflammatory, antiviral, anti-diabetic, neuroprotective, and antioxidant properties. Lentinan acts as a biological response modifier and immunostimulant, improving intestinal barrier integrity by enhancing tight junction proteins, restoring redox balance, and reducing serum lipopolysaccharide levels. Lentinan modulates cell signaling and immune responses through β-glucan-responsive receptors like dectin-1, complement receptor 3, lactosylceramide, and TLRs, showing efficacy in treating various conditions including hepatitis, HIV, and certain cancers.

Disclaimer

Hygroscopic, Store with desiccant


Storage Class

11 - Combustible Solids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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