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MilliporeSigma

SML4484

Hydroxyprogesterone caproate

≥98% (HPLC)

Synonym(s):

17α-Hydroxyprogesterone hexanoate, 17-α-Hydroxyprogesterone caproate, 17-Caproxyprogesterone, 17-HPC, 17-OHPC, 17-[(1-Oxohexyl)oxy]pregn-4-ene-3,20-dione

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About This Item

Empirical Formula (Hill Notation):
C27H40O4
CAS Number:
Molecular Weight:
428.60
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

17-α-Hydroxyprogesterone caproate (17-OHPC) is a selective, long-acting progesterone receptor agonist, mimicking natural progesterone with minimal other hormonal activity. Administered intramuscularly in oil, it offers improved pharmacokinetics and sustained plasma concentrations, primarily metabolized by CYP3A4/5. 17-OHPC activates progesterone-responsive genes, reducing uterine contractility and maintaining cervical integrity, potentially via anti-inflammatory effects, notably by increasing IL-10 production.


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Pictograms

Health hazard

Signal Word

Danger

Hazard Codes

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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