Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C16H17ClN2O4
CAS Number:
Molecular Weight:
336.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
Clonixeril (CXL) is a cell-permeable non-nucleotide that uniquely modulates hSTING, acting as either a weak partial agonist or a highly potent antagonist. Its antagonistic mechanism—blocking STING oligomerization and phosphorylation (Ser366)—is critically dependent on pre-agonist administration, as it cannot reverse pre-formed, disulfide-stabilized oligomers. Consequently, Clonixeril employs a non-classical, non-stoichiometric mechanism distinct from simple competitive antagonism.
Storage Class
11 - Combustible Solids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.