UC441
6´,-7´-Dihydroxybergamottin
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 mg | 0 left in stock | $988.00 |
About This Item
Empirical Formula (Hill Notation):
C21H24O6
CAS Number:
Molecular Weight:
372.41
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12161501
MDL number:
Form:
solid
Quality level:
form
solid
Quality Level
color
white to light beige
solubility
ethanol: soluble
storage temp.
2-8°C
SMILES string
C\C(CCC(O)C(C)(C)O)=C/COc1c2C=CC(=O)Oc2cc3occc13
InChI
1S/C21H24O6/c1-13(4-6-18(22)21(2,3)24)8-10-26-20-14-5-7-19(23)27-17(14)12-16-15(20)9-11-25-16/h5,7-9,11-12,18,22,24H,4,6,10H2,1-3H3/b13-8+
InChI key
IXZUPBUEKFXTSD-MDWZMJQESA-N
Application
6′,7′-dihydroxybergamottin has been used to study its effect on the inhibition of cytochrome P450 (CYP)-mediated triazolam hydroxylation in dog liver microsomes[1].
Biochem/physiol Actions
CYP3A4 inhibitor.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Preparation Note
6′,-7′-Dihydroxybergamottin is soluble in ethanol and can be further diluted with water.
1 of 1
This Item | |||
|---|---|---|---|
| form solid | form solid | form solid | form solid |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility ethanol: soluble | solubility H2O: soluble, methanol: soluble | solubility methanol: soluble | solubility methanol: soluble |
| color white to light beige | color white to off-white | color white to pink | color off-white |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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M J Hanley et al.
Journal of veterinary pharmacology and therapeutics, 33(2), 189-195 (2010-05-07)
Coadministration of grapefruit juice (GFJ) has been proposed to enhance the systemic availability and decrease the required dose of drugs such as cyclosporine that are extensively metabolized in the intestine and liver. Although GFJ inhibits human cytochrome P450 (CYP) 3A
Global Trade Item Number
| SKU | GTIN |
|---|---|
| UC441-5MG | 04061837410277 |
| UC441-10MG | 04061832932262 |