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T Beta-Cyanoethyl Phosphoramidite

Name: T Beta-Cyanoethyl Phosphoramidite
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

(5′-O-Dimethoxytritylthymidine-3′-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)

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About This Item

Empirical Formula (Hill Notation):

C₄₀H₄₉N₄O₈P

CAS Number:

98796-51-1

Molecular Weight:

744.81

MDL number:

MFCD00055063

UNSPSC Code:

41116107

NACRES:

NA.24

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Properties

grade

pharmaceutical primary standard

agency

USP

form

powder

manufacturer/tradename

USP

application(s)

USP Biologics
pharmaceutical

format

neat

storage temp.

−20°C

SMILES string

P(N(C(C)C)C(C)C)(O[C@@H]1[C@H](O[C@H](C1)[n]5[c]([nH][c](c(c5)C)=O)=O)COC(c4ccc(cc4)OC)(c3ccc(cc3)OC)c2ccccc2)OCCC#N

InChI

1S/C40H49N4O8P/c1-27(2)44(28(3)4)53(50-23-11-22-41)52-35-24-37(43-25-29(5)38(45)42-39(43)46)51-36(35)26-49-40(30-12-9-8-10-13-30,31-14-18-33(47-6)19-15-31)32-16-20-34(48-7)21-17-32/h8-10,12-21,25,27-28,35-37H,11,23-24,26H2,1-7H3,(H,42,45,46)/t35-,36+,37+,

InChI key

UNOTXUFIWPRZJX-CEXSRUIHSA-N

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This compound is a thymidine phosphoramidite, utilized in DNA synthesis to introduce thymidine units into oligonucleotides.

The USP biologics oligonucleotides category includes a variety of synthetic nucleic acid sequences that are essential in research, diagnostics, and therapeutic applications. These oligonucleotides play crucial roles in molecular biology, including gene expression regulation, antisense therapy, and RNA interference. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of oligonucleotide products throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

This product is part of USP Biologics Program.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

USP issued SDS can be found here

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This Item	T111030	T111080	T111050
USP 1152031 T Beta-Cyanoethyl Phosphoramidite	Sigma-Aldrich T111030 DMT-dT Phosphoramidite	Sigma-Aldrich T111080 DMT-dT Phosphoramidite	Sigma-Aldrich T111050 DMT-dT Phosphoramidite
description United States Pharmacopeia (USP) Reference Standard	description configured for ABI	description configured for PerkinElmer, configured for Polygen	description configured for ÄKTA^® and OligoPilot^®
manufacturer/tradename USP	manufacturer/tradename -	manufacturer/tradename -	manufacturer/tradename -
grade pharmaceutical primary standard	grade -	grade -	grade -
application(s) USP Biologics pharmaceutical	application(s) -	application(s) -	application(s) -
format neat	format -	format -	format -
form powder	form powder or granules	form powder or granules	form powder or granules
agency USP	agency -	agency -	agency -

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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