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ADRB2

adrenoceptor beta 2, surface

Synonyme:
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(154) Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11555) adrenergic receptor, beta 2
  • Rat(24176) adrenoceptor beta 2, surface
  • cow(281605) adrenergic, beta-2-, receptor, surface
  • Horse(100060659) adrenoceptor beta 2, surface
  • domestic cat(493767) adrenoceptor beta 2, surface
  • naked mole-rat(101708921) adrenoceptor beta 2, surface
  • domestic guinea pig(100722663) adrenoceptor beta 2, surface
  • dog(403910) adrenoceptor beta 2, surface
  • chicken(427623) adrenergic, beta-2-, receptor, surface
  • Domestic Rabbit(100340821) adrenoceptor beta 2, surface
  • sheep(100170320) adrenoceptor beta 2, surface

Custom & Knockdown Gene Products

Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
(−)-Isoproterenol -hydrochlorid, ,
Spezies
human
Clenbuterol -hydrochlorid, ≥95%,
Spezies
human
Salbutamol, ,
Spezies
human
Formoterol -fumarat Dihydrat, >98% (HPLC),
Spezies
human
Albuterolsulfat, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
ICI 118.551 -hydrochlorid, ≥98% (HPLC), powder,
Spezies
human
Propranolol-Hydrochlorid, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Propranolol -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Nadolol, analytical standard,
Spezies
human
Timololmaleat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-ADRB2 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

western blot
Anti-β2-Adrenergic Receptor Antibody, clone 2B23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human
Anwendung
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-ADRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-Adrenergic Receptor β2 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-Adrenergic Receptor B2 (pSer355+Ser356) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry

western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Sotalol -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Sotalol -hydrochlorid, British Pharmacopoeia (BP) Reference Standard,
Spezies
human
(±)-Sotalol -hydrochlorid, ≥98% (TLC), powder,
Spezies
human
(S)-(−)-Propranolol -hydrochlorid, ≥98% (TLC), powder,
Spezies
human
Propafenon -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human ADRB2,
Spezies
human
MISSION® esiRNA, targeting mouse Adrb2,
Spezies
mouse