C5423

Clenbuterol -hydrochlorid

≥95% (TLC), powder, β2-adrenoceptor agonist

• Synonym(e): 4-Amino-α-(tert.-butylaminomethyl)-3,5-dichlorbenzylalkohol -hydrochlorid
• Empirische Formel (Hill-System): C₁₂H₁₈Cl₂N₂O · HCl
• CAS-Nummer: 21898-19-1
• Molekulargewicht: 313.65
• NACRES: NA.77
• PubChem Substance ID: 24892782
• UNSPSC Code: 12352200
• EC Number: 244-643-7
• MDL number: MFCD00083280
• Assay: ≥95%
• Form: powder

Eigenschaften

• Produktname: Clenbuterol -hydrochlorid, ≥95%
• Quality Segment: 200
• assay: ≥95%
• form: powder
• drug control: Home Office Schedule 4.2
• storage temp.: 2-8°C
• SMILES string: Cl.CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1
• InChI: 1S/C12H18Cl2N2O.ClH/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7;/h4-5,10,16-17H,6,15H2,1-3H3;1H
• InChI key: OPXKTCUYRHXSBK-UHFFFAOYSA-N
• Gene Information: human ... ADRB2(154)

Beschreibung

Application

Clenbuterol hydrochloride has been used:

• as an agonist for β-adrenergic receptor (β-AR) from chick skeletal muscle
• to induce hypertrophic effects in masseter, digastric, and temporalis muscles of rat
• as a reference β-agonist standard in tandem mass spectrometry(MS-MS)

Biochem/physiol Actions

Clenbuterol hydrochloride is a β2-adrenoceptor agonist and bronchodilator. It is effective in improving peak expiratory flow rate (PEFR) in asthma patients. Clenbuterol is also a performance-enhancing drug as it stimulates the central nervous system and improves oxygen transport. Clenbuterol elicits cardio protective functionality in patients with dilated cardiomyopathy.

Sicherheitshinweise

• Signalwort: Danger
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Piktogramme: GHS06,GHS08
• Gefahrencodes: H301,H351,H360FD
• Sicherheitshinweise: P202 - P264 - P280 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 2 - Repr. 1B