CHRNA3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
Synonyme:
LNCR2, NACHRA3, PAOD2
Spezies:
Human CHRNA3 (1136), Mouse Chrna3 (110834), Rat Chrna3 (25101), domestic guinea pig Chrna3 (100730977), naked mole-rat Chrna3 (101701279), sheep CHRNA3 (101123239), Domestic Rabbit CHRNA3 (100342666), dog CHRNA3 (482111), cow CHRNA3 (282702), domestic cat CHRNA3 (100037403) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(1136) Summary: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
- Mouse(110834) cholinergic receptor, nicotinic, alpha polypeptide 3
- Rat(25101) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- domestic guinea pig(100730977) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- naked mole-rat(101701279) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- sheep(101123239) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- Domestic Rabbit(100342666) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- dog(482111) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- cow(282702) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- domestic cat(100037403) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- Zebrafish(568467) cholinergic receptor, nicotinic, alpha 3
- chicken(386578) cholinergic receptor, nicotinic, alpha 3
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Small Molecule - Agonist
Produktnummer
Beschreibung
Spezies
(−)-Nikotin -Lösung, 1.0 mg/mL, analytical standard, for drug analysis,
Spezies
human, mouse, rat
Small Molecule - Antagonist
Produktnummer
Beschreibung
Spezies
(−)-Nikotin -Lösung, 1.0 mg/mL, analytical standard, for drug analysis,
Spezies
human, mouse, rat
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CHRNA3 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
dog, human, rabbit
Anwendung
western blot
Monoclonal Anti-Nicotinic Acetylcholine Receptor (α1, α3, α5 Subunits) antibody produced in rat, clone mAb 35, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
chicken, eel, human
Anwendung
immunohistochemistry