37019

Atropin

analytical standard

• Synonym(e): (±)-Tropintropat, endo-(±)-α-(Hydroxymethyl)-benzolessigsäure-8-methyl-8-azabicyclo[3.2.1]oct-3-ylester, Hyoscyamin
• Empirische Formel (Hill-System): C₁₇H₂₃NO₃
• CAS-Nummer: 51-55-8
• Molekulargewicht: 289.37
• EC Number: 200-104-8
• UNSPSC Code: 85151701
• NACRES: NA.24
• PubChem Substance ID: 329755584
• Beilstein/REAXYS Number: 91260
• MDL number: MFCD00022622

Eigenschaften

• grade: analytical standard
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): cleaning products; cosmetics; food and beverages; personal care
• format: neat
• storage temp.: −20°C
• SMILES string: CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3
• InChI: 1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?
• InChI key: RKUNBYITZUJHSG-SPUOUPEWSA-N
• Gene Information: human ... CHRM1(1128), CHRM2(1129), CHRM3(1131)

Beschreibung

General description

Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.

Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.
For the analysis of the phytotoxins.

Application

Atropine may be used as a reference standard for the determination of atropine in:

• Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).
• Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.
• Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
• Plant materials by liquid-liquid extraction and EXtrelut^® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Atropine may be used as a reference standard for the determination of atropine in:

• Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).
• Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.
• Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
• Plant materials by liquid-liquid extraction and EXtrelut^® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.

Biochem/physiol Actions

Kompetitiver nichtselektiver Antagonist an zentralen und peripheren muskarinischen Acetylcholin-Rezeptoren.

Preparation Note

Dried down, 100 μg/mL nach Rücklösen in 1 mL Wasser

Analysis Note

purity : ≥96.0% (HPLC)

Legal Information

Extrelut is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• Gefahrencodes: H300 + H330
• Sicherheitshinweise: P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Lagerklasse: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable