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C1240

Chlormethiazole hydrochloride

Name: Chlormethiazole hydrochloride
Brand: SIGMA

≥98% (HPLC), GABAA agonist, powder

Synonym(e):

4-methyl-5-(β-chloroethyl)thiazole hydrochloride, 5-(2-Chloroethyl)-4-methylthiazole hydrochloride, Clomethiazole hydrochloride, Somnevrin hydrochloride

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Über diesen Artikel

Empirische Formel (Hill-System):

C₆H₈ClNS · HCl

CAS-Nummer:

6001-74-7

Molekulargewicht:

198.11

UNSPSC Code:

12352200

PubChem Substance ID:

329774745

NACRES:

NA.77

MDL number:

MFCD00673948

Assay:

≥98% (HPLC)

Form:

powder

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Eigenschaften

Produktname

Chlormethiazole hydrochloride, ≥98% (HPLC), powder

description

Store desiccated

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

off-white

solubility

H₂O: soluble >10 mg/mL

originator

AstraZeneca

SMILES string

Cl.Cc1ncsc1CCCl

InChI

1S/C6H8ClNS.ClH/c1-5-6(2-3-7)9-4-8-5;/h4H,2-3H2,1H3;1H

InChI key

OFXYKSLKNMTBHK-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

GABA_A agonist; glycine receptor modulator.

Chlormethiazole serves as an anticonvulsant. It is useful in treating alcohol addiction and eclampsia. Chlormethiazole is also useful in treating convulsive status epilepticus. Long term administration of chlormethiazole leads to addiction to the drug.

Features and Benefits

This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.