N7261

Nortriptylin -hydrochlorid

≥98% (HPLC), norepinephrine and serotonin inhibitor, powder

• Synonym(e): 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yliden)-N-methyl-1-propanamin -hydrochlorid, Desmethylamitriptylin -hydrochlorid
• Empirische Formel (Hill-System): C₁₉H₂₁N · HCl
• CAS-Nummer: 894-71-3
• Molekulargewicht: 299.84
• NACRES: NA.77
• PubChem Substance ID: 24278107
• UNSPSC Code: 41116107
• EC Number: 212-973-0
• MDL number: MFCD00058024
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Nortriptylin -hydrochlorid, ≥98% (HPLC), powder
• Quality Segment: 200
• assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• solubility: ethanol: 100 mg/mL, H₂O: soluble
• originator: Eli Lilly
• SMILES string: Cl.CNCC\C=C1\c2ccccc2CCc3ccccc13
• InChI: 1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-11,20H,6,12-14H2,1H3;1H
• InChI key: SHAYBENGXDALFF-UHFFFAOYSA-N
• Gene Information: human ... HTR2A(3356), HTR2B(3357), HTR2C(3358), SLC6A2(6530), SLC6A4(6532)

Beschreibung

Biochem/physiol Actions

Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter (K_i = 3.4 nM) than the serotonin transporter (K_i = 161 nM). 5-HT₂ serotonin receptor antagonist.

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H302
• Sicherheitshinweise: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Faceshields, Gloves