SML4048

LEI-102

≥95% (HPLC)

• Synonym(e): 1-[[4-[5-Fluoro-6-[[(tetrahydro-2H-pyran-4-yl)amino]methyl]-2-pyridinyl]phenyl]methyl]-3-(2-methylpropyl)-2,4-imidazolidinedione
• Empirische Formel (Hill-System): C₂₅H₃₁FN₄O₃
• CAS-Nummer: 1228659-40-2
• Molekulargewicht: 454.54
• NACRES: NA.21
• UNSPSC Code: 12352203
• Assay: ≥95% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C(N1CC(C)C)N(CC2=CC=C(C=C2)C3=CC=C(C(CNC4CCOCC4)=N3)F)CC1=O

Beschreibung

Biochem/physiol Actions

Orally available potent and selective cannabinoid CB2 receptor agonist.
LEI-102 is orally available, highly potent and highly selective cannabinoid CB2 receptor agonist. LEI-102 attenuates cisplatin-induced nephrotoxicity in mice. LEI-102 did not generate CB1R-mediated CNS-side effects at doses up to 25mg/kg (p.o.) in mice model.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H302,H315
• Sicherheitshinweise: P264 - P280 - P301 + P312 - P302 + P352 - P332 + P313 - P362 + P364
• Hazard Classifications: Acute Tox. 4 Oral - Skin Irrit. 2
• Lagerklasse: 11 - Combustible Solids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable