SML4446

LDM

≥98% (HPLC)

• Synonym(e): DCOH-FR-Ocl, LDM lipid droplet probe, O-[4-[2-[3-(Dicyanomethylene)-5,5-dimethyl-1-cyclohexen-1-yl]ethenyl]phenyl] N,N-dimethylcarbamothioate
• Empirische Formel (Hill-System): C₂₂H₂₃N₃OS
• CAS-Nummer: 2408641-99-4
• Molekulargewicht: 377.50
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C

Beschreibung

Biochem/physiol Actions

LDM is a cell penetrant lipid droplets fluorescent probe that selectively visualize the neutral lipid core of lipid droplets (LDs). LDM is activated by the HClO/ClO- present in the lipid droplets microenvironment to generate LDM-OH which selectively visualizes lipid droplet (LD) membrane by binding to LD associated proteins through electrostatic interactions. The HClO/ClO- activation transforms the green fluorescent pro-probe LDM (emission at 522 nm) to a red fluorescent LDM-OH (far-red emission at 637 nm). Also LDM (DCOH-FR-OCl) can be effectively utilized in the real-time imaging of endogenous and exogenous OCl- in living cells.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H302,H315
• Sicherheitshinweise: P264 - P280 - P301 + P312 - P302 + P352 - P332 + P313 - P362 + P364
• Hazard Classifications: Acute Tox. 4 Oral - Skin Irrit. 2
• Lagerklasse: 11 - Combustible Solids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable