Delayed effects of 1,2-epoxypropyltrimethylammonium chloride on behavioral reactions in rats.

We studied immediate and delayed effects of intraventricular injection of 1,2-epoxypropyltrimethylammonium chloride on behavioral reactions in rats. Apomorphine-induced yawning increased and orientation and exploratory activity was improved 144 h postinjection, which indicates activation of the brain dopaminergic system during this period.