1H NMR investigations of inclusion complexes between beta-cyclodextrin and 1-hexadecanol.

1H NMR investigations of inclusion complexes between beta-cyclodextrin and 1-hexadecanol.

Current drug discovery technologies (2007-11-30)

Huiming Jiang, Shufen Zhang, Qinglin Guan, Chang Chen, Fan Gao, Yang Zhang

ZUSAMMENFASSUNG

The inclusion complex between beta-CD and 1-hexadecanol is synthesized and identified via (1)H NMR spectrum. The possible conformation of the inclusion complex is figured out. Via MM2 calculations, the possibility of complexation is verified.

MATERIALIEN

Produktnummer

Marke

Produktbeschreibung

258741

Sigma-Aldrich

1-Hexadecanol, ReagentPlus^®, 99%

68824

Supelco

Cetylalkohol, analytical standard

W255408

Sigma-Aldrich

1-Hexadecanol, ≥99%

PHR1133

Supelco

Cetylalkohol, Pharmaceutical Secondary Standard; Certified Reference Material

H6800

Sigma-Aldrich

1-Hexadecanol, 95%

C0990000

Cetylalkohol, European Pharmacopoeia (EP) Reference Standard