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Method for activation and recycling of trityl resins.

The Journal of organic chemistry (2012-07-20)
Itedale Namro Redwan, Morten Grøtli
ZUSAMMENFASSUNG

This note describes a rapid and mild strategy for the loading of alcohols and anilines onto a polystyrene triphenylmethyl (trityl) resin. High loadings were obtained in a matter of minutes by treating resin-bound trityl chloride with triethyloxonium tetrafluoroborate followed by alcohols or anilines. Yields were comparable or better than known literature methods. Recycling of the recovered resin was also possible using the developed method.

MATERIALIEN
Produktnummer
Marke
Produktbeschreibung

Sigma-Aldrich
Tritylchlorid, 97%
Sigma-Aldrich
Triethyloxoniumtetrafluoroborat, ≥97.0% (T)
Sigma-Aldrich
Triethyloxoniumtetrafluorborat -Lösung, 1.0 M in methylene chloride
Sigma-Aldrich
Tritylchlorid, purum, ≥97.0% (HPLC), ≥97.0% (AT)