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Merck

S4500

L-Serine

≥99% (HPLC), ReagentPlus®

Synonym(s):

(S)-2-Amino-3-hydroxypropionic acid

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€ 22,70

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€ 182,00

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€ 1.680,00

€ 22,70


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About This Item

Linear Formula:
HOCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
105.09
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
NACRES:
NA.26
EC Number:
200-274-3
MDL number:
Beilstein/REAXYS Number:
1721404

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Product Name

L-Serine, ReagentPlus®, ≥99% (HPLC)

InChI key

MTCFGRXMJLQNBG-REOHCLBHSA-N

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

SMILES string

N[C@@H](CO)C(O)=O

product line

ReagentPlus®

assay

≥99% (HPLC)

form

powder

color

white to off-white

mp

222 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

application(s)

detection

storage temp.

room temp

Quality Level

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1 of 4

This Item
5476316125061.07647
form

powder

form

-

form

-

form

crystalline powder

assay

≥99% (HPLC)

assay

-

assay

-

assay

-

product line

ReagentPlus®

product line

TraceCERT®

product line

-

product line

EMPROVE® EXPERT

storage temp.

room temp

storage temp.

-

storage temp.

-

storage temp.

2-30°C

solubility

H2O: 50 mg/mL, clear, colorless

solubility

-

solubility

-

solubility

360 g/L

mp

222 °C (dec.) (lit.)

mp

222 °C (dec.) (lit.)

mp

222 °C (dec.) (lit.)

mp

215-225 °C (decomposes)

Application

L-Serine has been used in the preparation of Tris-BSAN buffer for homogenization. It has also been used for quantitative analysis of excretion of polypeptides in normal urine.[1][2]

Biochem/physiol Actions

L-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system.[3] L-Serine also has a role in cellular proliferation.[4]
Precursor of glycine by serine hydroxymethyltransferase.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Quantitative amino acid and proteomic analysis: Very low excretion of polypeptides >750 Da in normal urine
Anthony G.W.Norden
Kidney International, 66(5) (2004)
Abel Lajtha, Simo S. Oja, Pirjo Saransaari, Arne Schousboe
Handbook of Neurochemistry and Molecular Neurobiology: Amino Acids and Peptides in the Nervous System , 4 (2007)
Analysis of GSH and GSSG after derivatization with N-ethylmaleimide
Nature Protocols, 8(9) (2003)
L-Serine in disease and development
Tom J. de Koning
Biochemistry, 371 (2003)
Taiga Okumura et al.
Scientific reports, 8(1), 9707-9707 (2018-06-28)
Radiocesium-bearing microparticles (CsPs) substantially made of silicate glass are a novel form of radiocesium emitted from the broken containment vessel of Fukushima Dai-ichi nuclear power plant. CsPs have a potential risk of internal radiation exposure caused by inhalation. Radiation-contaminated waste

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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