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Merck

79593

(−)-Bilobalide

analytical standard

Synonym(s):

Bilobalide

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10 MG

$599.00

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About This Item

Empirical Formula (Hill Notation):
C15H18O8
CAS Number:
33570-04-6
Molecular Weight:
326.30
MDL number:
MFCD00132880
UNSPSC Code:
85151701
PubChem Substance ID:
329768523
NACRES:
NA.24

Key Documents

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grade

analytical standard

Quality Level

100

Assay

≥96.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

CC(C)(C)[C@]1(O)C[C@@H]2OC(=O)C[C@]23C(=O)O[C@@H]4OC(=O)[C@H](O)C134

InChI

1S/C15H18O8/c1-12(2,3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13,14)8(17)9(18)22-11/h6,8,11,17,20H,4-5H2,1-3H3/t6-,8-,11-,13+,14+,15?/m0/s1

InChI key

MOLPUWBMSBJXER-DXPZGIEZSA-N

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1 of 4

This Item
9497018309B9031
(−)-Bilobalide analytical standard

Supelco

79593

(−)-Bilobalide

Ginkgolide B analytical standard

Supelco

94970

Ginkgolide B

Ginkgolide C analytical standard

Supelco

18309

Ginkgolide C

(−)-Bilobalide from Ginkgo biloba leaves ≥93% (HPLC)

Sigma-Aldrich

B9031

(−)-Bilobalide from Ginkgo biloba leaves

application(s)

food and beverages

application(s)

food and beverages

application(s)

food and beverages

application(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

grade

analytical standard

grade

analytical standard

grade

analytical standard

grade

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

assay

≥96.0% (HPLC)

assay

-

assay

≥96.0% (HPLC)

assay

≥93% (HPLC)

General description

(−)-Bilobalide is a Ginkgo terpenoid, available as the main pharmacological component in Ginkgo biloba extract.[1] It exhibits neuroprotectant activity.[1]

Application

(−)-Bilobalide may be used as an analytical rstandard for the quantification of the analyte in biological samples using liquid chromatography coupled to tandem mass spectrometry.[2]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: ginkgo

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF6980V
WXBF6263V
WXBF4995V
BCCL4788
BCCK1717

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Jiangang Shen et al.
Chinese medicine, 6, 8-8 (2011-02-25)
EGb761 is a standard extract from the leaves of Ginkgo biloba (Yinxing) containing ginkgo-flavone glycosides and terpenoid. The flavonoid components of EGb761 scavenge free radicals and protect myocardia from ischemia-reperfusion injury. The present study aims to determine the effects of
Simultaneous determination of ginkgolides A, B, C and bilobalide in plasma by LC-MS/MS and its application to the pharmacokinetic study of Ginkgo biloba extract in rats
Xie J, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 864(1-2), 87-94 (2008)
Vamsi L M Madgula et al.
Planta medica, 76(6), 599-606 (2009-11-26)
In this study intestinal and blood-brain barrier (BBB) permeability of ginkgolides A, B, C, J and bilobalide, isolated from Ginkgo biloba (Ginkgoaceae), was evaluated in Caco-2 and MDR1-MDCK cell monolayer models. The transport was examined for 2 hours in both
Alice C Rodrigues et al.
Biopharmaceutics & drug disposition, 32(6), 355-367 (2011-07-29)
Several noncoding microRNAs (miR or miRNA) have been shown to regulate the expression of drug-metabolizing enzymes and transporters. Xenobiotic drug-induced changes in enzyme and transporter expression may be associated with the alteration of miRNA expression. Therefore, this study investigated the
Limei Han et al.
Fitoterapia, 83(4), 721-731 (2012-03-15)
It is difficult to develop injectable sustained delivery systems for herbal medicines because of their composition complexity. Encapsulating various compounds with different physiochemical properties and achieving their synchronized and sustained release seem too hard to realize. In this paper, an
View All Related Papers

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