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Merck

A0773

Angiotensin Converting Enzyme Inhibitor

≥95% (TLC)

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$442.00

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About This Item

Empirical Formula (Hill Notation):
C53H76N14O12
CAS Number:
35115-60-7
Molecular Weight:
1101.26
NACRES:
NA.77
PubChem Substance ID:
329770629
UNSPSC Code:
12352200
MDL number:
MFCD00076208

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Product Name

Angiotensin Converting Enzyme Inhibitor, ≥95% (TLC)

InChI key

UUUHXMGGBIUAPW-CSCXCSGISA-N

SMILES string

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]5CCC(=O)N5)C(=O)N6CCC[C@H]6C(=O)N7CCC[C@H]7C(O)=O

InChI

1S/C53H76N14O12/c1-3-29(2)43(51(77)66-25-9-16-39(66)50(76)67-26-10-17-40(67)52(78)79)63-45(71)34(18-20-41(54)68)60-46(72)37-14-7-23-64(37)48(74)35(13-6-22-57-53(55)56)61-47(73)38-15-8-24-65(38)49(75)36(62-44(70)33-19-21-42(69)59-33)27-30-28-58-32-12-5-4-11-31(30)32/h4-5,11-12,28-29,33-40,43,58H,3,6-10,13-27H2,1-2H3,(H2,54,68)(H,59,69)(H,60,72)(H,61,73)(H,62,70)(H,63,71)(H,78,79)(H4,55,56,57)/t29-,33-,34-,35-,36-,37-,38-,39-,40-,43-/m0/s1

biological source

synthetic (organic)

assay

≥95% (TLC)

form

powder

mol wt

~_1.1 kDa

solubility

water: soluble 1 mg/mL, clear, colorless

storage temp.

−20°C

Quality Level

200

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1 of 4

This Item
A6185A0230P7340
Angiotensin Converting Enzyme Inhibitor ≥95% (TLC)

Sigma-Aldrich

A0773

Angiotensin Converting Enzyme Inhibitor

Calpain Inhibitor I ≥97% (TLC), powder

Sigma-Aldrich

A6185

Calpain Inhibitor I

Angiotensin IV trifluoroacetate salt ≥95% (HPLC), powder

Sigma-Aldrich

A0230

Angiotensin IV trifluoroacetate salt

(±)-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol hydrochloride

Sigma-Aldrich

P7340

(±)-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol hydrochloride

form

powder

form

powder

form

powder

form

powder

assay

≥95% (TLC)

assay

≥97% (TLC)

assay

≥95% (HPLC)

assay

≥98% (TLC)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

mol wt

~_1.1 kDa

mol wt

-

mol wt

-

mol wt

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

water: soluble 1 mg/mL, clear, colorless

solubility

DMSO: soluble, ethanol: soluble

solubility

H2O: ~1 mg/mL

solubility

water: 50 mg/mL, clear, colorless

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000496363
0000496363
SLCH1799
0000461906
0000456411

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R Matsas et al.
The Biochemical journal, 223(2), 433-440 (1984-10-15)
Endopeptidase-24.11 (EC 3.4.24.11), purified to homogeneity from pig kidney, was shown to hydrolyse a wide range of neuropeptides, including enkephalins, tachykinins, bradykinin, neurotensin, luliberin and cholecystokinin. The sites of hydrolysis of peptides were identified, indicating that the primary specificity is
Linqing Ma et al.
Journal of Alzheimer's disease : JAD, 27(1), 225-237 (2011-07-30)
Apomorphine hydrochloride (APO) is known to be a dopamine receptor agonist, and has recently been found to be a novel drug for Alzheimer's disease (AD). We found that APO treatment ameliorated oxidative stress in an AD mouse model and specifically
Daniela A P Cidade et al.
Toxicon : official journal of the International Society on Toxinology, 48(4), 437-461 (2006-08-15)
Bothrops jararaca is a pit viper responsible for the majority of snake envenoming accidents in Brazil. As an attempt to describe the transcriptional activity of the venom gland, ESTs of a cDNA library constructed from B. jararaca venom gland were
Mark Fahey et al.
The Journal of rheumatology, 36(1), 163-169 (2009-01-10)
Calcium pyrophosphate dihydrate (CPPD) crystals are commonly found in osteoarthritic joints and correlate with a poor prognosis. Intraarticular corticosteroids, such as dexamethasone (Dxm), are commonly used therapies for osteoarthritis with or without CPPD deposition. Dxm has variable effects in mineralization
Karly C Sourris et al.
American journal of nephrology, 30(4), 323-335 (2009-06-27)
A commonality among the chemically disparate compounds that inhibit the formation and accumulation of advanced glycation end products (AGEs) or their signalling pathways is their end organ protection in experimental models of diabetes complications. Although this group of therapeutics are
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