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Merck

1.47574

di-Sodium hydrogen phosphate heptahydrate

granulated, DAC, USP, EMPROVE® EXPERT

Synonym(s):

Sodium phosphate dibasic heptahydrate, Disodium hydrogen phosphate heptahydrate, Disodium phosphate

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1 KG

€87.40

25 KG

€950.00

500 KG

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€87.40


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About This Item

Linear Formula:
Na2HPO4 · 7H2O
CAS Number:
Molecular Weight:
268.07
MDL number:
UNSPSC Code:
12352200
Form:
granular

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Agency

DAC
USP

Quality Level

vapor density

4.9 (vs air)

product line

EMPROVE® EXPERT

form

granular

impurities

low in endotoxins

density

1.68 g/mL at 25 °C (lit.)

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharma/biopharma processes
pharma/biopharma processes

storage temp.

15-25°C

SMILES string

O.O.O.O.O.O.O.[Na+].[Na+].OP([O-])([O-])=O

InChI

1S/2Na.H3O4P.7H2O/c;;1-5(2,3)4;;;;;;;/h;;(H3,1,2,3,4);7*1H2/q2*+1;;;;;;;;/p-2

InChI key

PYLIXCKOHOHGKQ-UHFFFAOYSA-L

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1 of 4

This Item
1.370921.06574S9390
form

granular

form

solid

form

solid

form

powder

Quality Level

500

Quality Level

500

Quality Level

500

Quality Level

200

density

1.68 g/mL at 25 °C (lit.)

density

1.68 g/mL at 25 °C (lit.)

density

1.68 g/mL at 25 °C (lit.)

density

1.68 g/mL at 25 °C (lit.)

impurities

low in endotoxins

impurities

-

impurities

-

impurities

≤0.005% Insoluble matter

agency

DAC

agency

DAC, USP

agency

DAC, USP

agency

-

vapor density

4.9 (vs air)

vapor density

4.9 (vs air)

vapor density

4.9 (vs air)

vapor density

4.9 (vs air)

General description

Standard bulk materials often show a tendency for caking, clumping and dust formation which results in laborious weighing and manual de-caking processes with a negative impact on manufacturing efficiency. Due to its granulated form, di-Sodium hydrogen phosphate heptahydrate granulated is free-flowing and easy to handle. Its greatly reduced caking behavior facilitates processability, speeds up manufacturing processes and increases operator safety. As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

di-Sodium hydrogen phosphate heptahydrate is used as a buffer component for Biomolecule downstream processing steps and final formulation as well as small molecule final formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Articles

Handling bulk powders at a large scale in the pharmaceutical, biopharmaceutical, and bioprocessing setting is challenging. Compared to powders, granulated materials experience far less caking, have better flowability, and are easier to handle, even after long-term storage.

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