AB16982
Anti-Fas Antibody
CHEMICON®, rabbit polyclonal
Synonym(s):
FasL
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50 μG
€439.00
€439.00
Estimated to ship on18 February 2026Details
A recombinant, preservative-free antibody is available for your target. Try ZRB2342
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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Product Name
Anti-Fas Ligand Antibody, Chemicon®, from rabbit
biological source
rabbit
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, mouse, rat
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... FAS(355)
1 of 4
This Item | SAB2105218 | WH0000355M5 | MAB3061 |
|---|---|---|---|
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| antibody form affinity purified immunoglobulin | antibody form affinity isolated antibody | antibody form purified immunoglobulin | antibody form purified immunoglobulin |
| biological source rabbit | biological source rabbit | biological source mouse | biological source mouse |
| Gene Information human ... FAS(355) | Gene Information human ... FAS(355) | Gene Information human ... FAS(355) | Gene Information human ... FAS(355) |
| species reactivity human, mouse, rat | species reactivity human | species reactivity human | species reactivity human |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
Application
Research Sub Category
Apoptosis - Additional
Apoptosis - Additional
Anti-Fas Ligand Antibody detects level of Fas Ligand & has been published & validated for use in ELISA & WB.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Western Blotting: 1:1,000-1:5,000 Rat, mouse and human FASL have 278, 279, and 281 AA residues, respectively (calculated MW 32kDa). Western blot of the oocyte has detected a specific 31kDa band (Hakuno et al. 1996). A 40 kDa FASL has been detected in mouse T cells (Hahne 1995). An alternate detecting reagent, mFAS-Fc (Suda & Nagata 1994) also detected a cell surface protein of about 40 kDa.
ELISA: 0.5-1μg/mL
Optimal working dilutions must be determined by the end user.
ELISA: 0.5-1μg/mL
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Human FAS Ligand (FASL). The 13-mer human FASL sequence used for antibody production is 92% (12/13 AA) homologous with rat and mouse FASL. Based upon the sequence homology data, anti-human FASL will likely cross react with the mouse/rat FASL.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
A 13 AA peptide sequence mapping near the C-terminus of human FAS ligand (Mita et al. 1994). This peptide is predicted to be extracellular. The peptide was synthesized with C-terminal Cysteine, coupled to KLH.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Peptide affinity purified immunoglobulin. Liquid in PBS, containing 0.1% BSA.
Preparation Note
Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Prenatal exposure of mice to diethylstilbestrol disrupts T-cell differentiation by regulating Fas/Fas ligand expression through estrogen receptor element and nuclear factor-?B motifs.
Singh, NP; Singh, UP; Nagarkatti, PS; Nagarkatti, M
Journal of Pharmacology and Experimental Therapeutics null
Lihong Chen et al.
Immunology and cell biology, 97(8), 714-725 (2019-04-13)
Acute rejection is the major determinant for the long-term survival of donor liver after liver transplantation (LT). The aim of this study was to examine the therapeutic potential of interleukin (IL)-10-FasL-overexpressing immature dendritic cells (imDCs) to induce local immunosuppression in
Sisi Wu et al.
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Elena Beltramo et al.
Acta ophthalmologica, 96(1), e19-e26 (2017-01-28)
Loss of pericytes is one the key events in the pathogenesis of diabetic retinopathy. We have previously demonstrated that human retinal pericytes (HRP) are more vulnerable to intermittent than stable high glucose concentrations, with an increase in apoptosis. Our aim
Yi Peng et al.
Cell death & disease, 11(5), 317-317 (2020-05-07)
Mesenchymal stem cell (MSC) therapy is a promising approach against myocardial infarction (MI). Studies have demonstrated that MSCs can communicate with other cells by secreting exosomes. In the present study, we aimed to identify exosomal microRNAs that might contribute to
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